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Simulación del proceso de producción de L-fenilalanina por la ruta fermentativa utilizando el simulador SuperPro Designer®

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dc.contributor.authorPerez Sanchez, Amauryspa
dc.contributor.authorRanero-González, Elizabethspa
dc.contributor.authorPérez-Sánchez, Eddy J.spa
dc.contributor.authorSegura-Silva, Rutdali Mariaspa
dc.date.accessioned2020-12-31 14:30:36
dc.date.accessioned2022-06-17T20:20:51Z
dc.date.available2020-12-31 14:30:36
dc.date.available2022-06-17T20:20:51Z
dc.date.issued2020-12-31
dc.description.abstractLa L-fenilalanina (L-Fe) es uno de los ocho aminoácidos esenciales para el cuerpo humano. En el presente trabajo se efectuó la simulación del proceso de producción de la L-Fe por la ruta fermentativa mediante el simulador SuperPro Designerâ, con el fin de conocer sus indicadores de rentabilidad más importantes bajo las condiciones económicas actuales de Cuba. También se efectuó un estudio de sensibilidad con el objetivo de saber a partir de qué valor del parámetro precio de venta unitario del frasco de L-Fe se comienza a obtener un valor positivo del indicador Valor Actual Neto (VAN). Se obtuvo un margen bruto de 70,15 %, un costo unitario de producción de USD $ 66,75 por frasco y un retorno de la inversión de 38,92 %. A partir de un valor del precio de venta unitario del frasco de L-Fe de USD $ 115,3 empieza a ser rentable la planta de producción. El proceso de producción de L-Fe puede considerarse de rentable y factible desde el punto de vista técnico-económico atendiendo a los resultados obtenidos de VAN (USD $ 14 040 000), Tasa Interna de Retorno (49,14 %) y Período de Recuperación de la Inversión (2,57 años).spa
dc.description.abstractL-phenylalanine (L-Phe) is one of the eight essential amino acids for the human body. In this work, the simulation of the L-Phe fermentative production process was carried out using the SuperPro Designer® simulator, in order to know its most important profitability indicators under the current economic conditions in Cuba. A sensitivity study was also accomplished with the objective of knowing from which value of the parameter unit selling price of an L-Phe bottle a positive value begins to be obtained of the indicator Net Present Value (NPV). A gross margin of 70.15%, a unit cost of production of USD $ 66.75 per bottle and a return on investment of 38.92% were obtained. From a value of the unit sale price of the L-Phe bottle of USD $ 115.3 the production plant starts to be profitable. The L-Phe production process can be considered profitable and feasible from the techno-economical point of view, based on the results obtained of NPV (USD $ 14,040,000), Internal Rate of Return (49.14%) and Payback Time (2.57 years).     eng
dc.format.mimetypeapplication/pdfspa
dc.identifier.doi10.24050/reia.v18i35.1417
dc.identifier.eissn2463-0950
dc.identifier.issn1794-1237
dc.identifier.urihttps://repository.eia.edu.co/handle/11190/5119
dc.identifier.urlhttps://doi.org/10.24050/reia.v18i35.1417
dc.language.isospaspa
dc.publisherFondo Editorial EIA - Universidad EIAspa
dc.relation.bitstreamhttps://revistas.eia.edu.co/index.php/reveia/article/download/1417/1403
dc.relation.citationeditionNúm. 35 , Año 2021spa
dc.relation.citationendpage15
dc.relation.citationissue35spa
dc.relation.citationstartpage35017 pp. 1
dc.relation.citationvolume18spa
dc.relation.ispartofjournalRevista EIAspa
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dc.rightsRevista EIA - 2020spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
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dc.rights.creativecommonsEsta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0.spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0spa
dc.sourcehttps://revistas.eia.edu.co/index.php/reveia/article/view/1417spa
dc.subjectEstudio de sensibilidadspa
dc.subjectL-Fenilalaninaspa
dc.subjectFermentaciónspa
dc.subjectRentabilidadspa
dc.subjectSimulaciónspa
dc.subjectSuperPro Designerspa
dc.subjectSensitivity studyeng
dc.subjectL-Phenylalanineeng
dc.subjectFermentationeng
dc.subjectProfitabilityeng
dc.subjectSimulation; SuperPro Designer®eng
dc.titleSimulación del proceso de producción de L-fenilalanina por la ruta fermentativa utilizando el simulador SuperPro Designer®spa
dc.title.translatedSimulation of the L-phenylalanine production process by the fermentative route using SuperPro Designer® simulatoreng
dc.typeArtículo de revistaspa
dc.typeJournal articleeng
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dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
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